Familial progressive cardiac conduction disorder and multiple exostoses.

Familial cardiac conduction disorder of a progressive nature has been reported in adult and paediatric patients. An underlying cardiomyopathy was found in most of these patients, either of hypertrophic, restrictive or dilated variety. Systemic diseases like juvenile rheumatoid arthritis and other collagen disorders and familial dysautonomia infrequently have associated conduction abnormalities. We present a family in which four of seven siblings had abnormalities of cardiac conduction and no concomitant cardiomyopathy or systemic disease. Additionally, there was an association of multiple bony exostoses in six siblings and deafness in two (Table I). The purpose of this presentation is to highlight the association of two familial abnormalities in one family.